New study estimates 75% of deceased ex-NFL players had brain disease CTE

Read the original at The Guardian ↗
Cite

Dunbar, M. (2026, October 28). New study estimates 75% of deceased ex-NFL players had brain disease CTE. The Guardian. https://www.theguardian.com/us-news/2026/oct/28/cte-nfl-brain-disease-research

Dated from the outlet's own feed. Check the original for its byline.

The Guardian · collected 2026-10-28 · by Marina Dunbar

Quick Summary

A new study published on Wednesday estimates that about 75% of former NFL players who died between 2008 and 2023 had chronic traumatic encephalopathy (CTE). The research, conducted by a Boston-based team and published in Jama Network Open, analyzed records from approximately 2,362 deceased former NFL players. Among the nearly 400 players whose brains were donated for examination, 93.5% showed evidence of CTE, significantly higher than the less than 1% rate observed in brain samples from the general population. The study aims to estimate the prevalence of CTE among all former NFL players who died during this period rather than limiting analysis to those who donated their brains for research.
Written by AI on 2026-10-29, from this article's own text only (the story summary below draws on all the coverage).

AI analysis

Story summary

A new study published in JAMA Network Open estimates that 75% of former NFL players who died between 2008 and 2023 had signs of chronic traumatic encephalopathy (CTE), a degenerative brain disease. The study, led by researchers from the Boston University Alzheimer’s Disease and CTE Center, analyzed records from 2,362 deceased former NFL players who spent an average of five years in the league. Of the nearly 400 brains donated for examination, 93.5% showed evidence of CTE. This finding is significantly higher than previous estimates, with a recent study in August estimating only one-quarter of players had CTE over a shorter time frame. Notably, about 27% of former players were estimated to have dementia, though the presence of CTE does not necessarily mean a person will develop cognitive decline or dementia. The NFL responded by stating they continuously strive to make football safer and reduce concussions and head impacts.

Written for “NFL Player Brain Disease Estimate Study” on 2026-10-29, grounded in this article and the 1 other(s) covering the same event.

Story

📰 NFL Player Brain Disease Estimate Study
Health · 2 article(s) covering the same event. See how they differ ↓

Compared with similar articles

This article reads unscored and hedges 15% of its claims. Each row says how that neighbour differs.
NBC News
Hedges 2 of 41 claims Outlet record 95/100
CBS News
Hedges 8 of 37 claims Outlet record 66/100
“While both articles discuss the same study about CTE prevalence among deceased NFL players, Article B focuses on expert reactions and additional context around the research, not just reporting the study itself.”
How this article was measured signals, leaning charts, publisher record, byline, topics and claims

Signals How these are calculated →

Claims extracted
20
sentences that state something as happening or true
Uncertain
15%
3 of 20 hedged ("reportedly", "may", "according to")
Leaning
not political
takes no side on a contested political question
Publisher signals
67/100
The Guardian's corrections and hedging, across everything collected from it. Not a measure of accuracy.
Outlets on this story
2
Health
Same framing elsewhere
1
articles that frame the event the way this one does
Analyzed 2026-10-29 · how these are computed

How this is being covered How these are calculated →

Article leaning vs. publisher reliability
Source leaning vs. consistency

Publisher

The Guardian · 1763 article(s) · 5 correction(s) detected
Running correction rate · 5 correction(s)

Who wrote this

Marina Dunbar
39 article(s) here · 1 carrying a prediction
🔮 However, the presence of CTE-related changes in the brain does not necessarily mean a person will develop dementia or experience declining cognitive abilities.
🔮 Pamela Reckamp, a 59-year-old resident of the ship, told NBC News that company officials on the ship had held a meeting last month where they asked cabin owners to help them raise $1m so the ship could depart Ha Long Bay, Vietnam.
🔮 Polls were initially set to close at 5pm Brasília time.
🔮 The family of a man who was ejected from a rollercoaster at a Six Flags amusement park in Georgia and died has publicly questioned whether the death could have been prevented.
🔮 Prosecutors had pushed for a minimum of 28 years, choosing that number to represent the age Jean would have reached at the time.
🔮 While the incident “may have directly involved only a few student team members”, the university’s recreation and wellness department moved to suspend the entire club indefinitely “pending an administrative investigation by the office of student conduct”, the statement said.
🔮 Two others were reported to be in critical condition, while the fourth was expected to survive, according to the Post’s sources.
🔮 So when the news broke in early 2026 that a real estate developer, Treetop Companies, was exploring plans for what could become one of the largest artificial intelligence (AI) datacenters in the country, a roughly 1-gigawatt campus spanning more than 1m sq ft across about 143 acres, it seemed the town would welcome a new phase in its technological evolution.
🔮 A former lawyer for Christa Pike says he was not surprised that Tennessee botched its attempt to execute her because attorneys had warned that problems accessing her veins could make the procedure dangerous and potentially cruel.
🔮 Frank Strada, the department of correction commissioner, will leave his position later in October as the state launches an independent investigation into what went wrong during Wednesday’s botched execution of Pike, according to Lee.
Also by Marina Dunbar
Nothing else under this byline is closely related to this article, so these are simply their most recent.
All 39 articles by Marina Dunbar →

Topics

Boston Jama Network Open Mass General NFL

Subjects

NFL ORG · 9× Aaron Hernandez PERSON · 1× Boston GPE · 1× Brigham PERSON · 1× Dave Duerson PERSON · 1× Jama Network Open ORG · 1× Junior Seau PERSON · 1× Mass General ORG · 1× Tripodis PERSON · 1× Yorghos Tripodis PERSON · 1×

Narrative

Following the publication of the earlier study, the NFL addressed its efforts to improve player safety in a statement: “The NFL continuously strives to make the game of football safer, including by implementing strategies to reduce concussions and head impacts.”
framing: assertive · carried by 1 article(s) · first seen 2026-10-29
🔮 However, the presence of CTE-related changes in the brain does not necessarily mean a person will develop dementia or experience declining cognitive abilities.
2026-10-29 · The Guardian
New study estimates 75% of deceased ex-NFL players had brain disease CTE · assertive framing

Claims (20 extracted, 3 hedged)

A new study published on Wednesday estimates that about 75% of former NFL players who died over a 15-year period had evidence of chronic traumatic encephalopathy (CTE). asserted
who → publish → encephalopathy
The research, published in Jama Network Open and conducted by a Boston-based team, examined the estimated prevalence of the degenerative brain disease among NFL players who died from 2008 through 2023. asserted
who → publish → 2023
Researchers found that the estimated rate of CTE among these players was substantially higher than the rates observed in brain samples collected from the general population. asserted
rate → find → population
The analysis included records from 2,362 deceased former NFL players who spent an average of five years in the league. asserted
who → include → league
Of the nearly 400 players whose brains were donated for examination, 93.5% showed evidence of CTE. asserted
% → donate → CTE
Researchers said the findings represented the first attempt to estimate how widespread CTE was among all former NFL players who died during the 2008-2023 period, rather than limiting the analysis to individuals whose brains were donated for research. asserted
brains → say → research
Physical changes associated with the condition include brain atrophy, which involves the loss of brain tissue, and accumulations of tau protein, a characteristic also associated with Alzheimer’s disease. asserted
which → associate → disease
The difference compared with the broader population was substantial. asserted
difference → compare → population
According to the study’s authors, less than 1% of brain samples from community-based brain banks contain evidence of CTE. uncertain
% → accord → CTE
However, the presence of CTE-related changes in the brain does not necessarily mean a person will develop dementia or experience declining cognitive abilities. asserted
person → relate → abilities
Some individuals with the condition may never develop noticeable symptoms. uncertain
individuals → develop → symptoms
Researchers estimated that approximately 27% of the former NFL players included in the analysis had dementia. asserted
% → estimate → dementia
CTE can also damage areas of the brain responsible for emotional control and behavior. asserted
CTE → damage → control
Potential symptoms include depression, memory problems, severe mood changes and other behavioral difficulties. asserted
symptoms → include → depression
“We recognize these findings may cause concern for the community of living players and their families,” Yorghos Tripodis, the study’s senior author, said in a statement released by Mass General Brigham. uncertain
Tripodis → recognize → Brigham
“We want them to know that we and others are standing by to provide support, and that we have hope for those living with CTE. asserted
we → want → CTE
“Discoveries from the brain bank have already brought us significantly closer to a diagnosis during life, at which point our most important goal will be to develop effective treatments for CTE,” Tripodis added. asserted
Tripodis → bring → CTE
The findings follow another study released in August, which determined that at least one in four of former NFL players who died between 2016 and 2021 had CTE. asserted
who → follow → CTE
Following the publication of the earlier study, the NFL addressed its efforts to improve player safety in a statement: “The NFL continuously strives to make the game of football safer, including by implementing strategies to reduce concussions and head impacts.” asserted
game → follow → concussions
A number of high-profile NFL players who took their own lives – including Junior Seau, Dave Duerson and Aaron Hernandez – were found to have had CTE when their brains were analyzed after their deaths. asserted
brains → take → deaths
💬Give feedback
🕘History 🎫Support