An Amazon cargo plane, operated by 21 Air, overran the runway at Miami International Airport on Sunday afternoon, crashing into several vehicles and bursting into flames. At least 5 people were killed and 10 others were injured, including 3 who are in critical condition and 2 with less severe injuries. The plane was arriving from San Juan, Puerto Rico and had been heading to Florida. It's not clear whether the pilots survived or how many of the victims were on board the plane or in vehicles when it struck. The incident has prompted an investigation by the National Transportation Safety Board, which is working with local authorities to determine the cause of the crash. The airport was shut down for several hours, causing disruptions to flights and travel plans.