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The San Francisco 49ers are facing injury concerns as they prepare to face the Seattle Seahawks in a crucial NFC West game. Key players like Mike Evans, who played through broken ribs against the Denver Broncos, might not fully participate due to lingering injuries but remain active and could play Sunday. Mykel Williams, recovering from a torn ACL, practiced on Thursday and seems set for his season debut. Meanwhile, Nick Bosa is expected to miss his third straight game with a calf injury. On a positive note, Christian McCaffrey and Trent Williams both participated in practice after resting Wednesday, indicating they should be ready for the matchup.
Written locally by qwen2.5:14b on 2026-10-08,
using this article's own text rather than the other coverage of the
same event (that is the story summary below).
Story summary
The San Francisco 49ers face an uncertain week as they deal with injuries ahead of their divisional matchup against the Seattle Seahawks on Sunday. Despite currently leading the NFC West, San Francisco was heavily defeated by Seattle in last year’s NFC Divisional Round playoff game. Key players like veteran wide receiver Mike Evans, who broke his ribs but played in a recent win over the Broncos with 76 receiving yards, remain questionable for Sunday's game after being limited at practice Wednesday. Meanwhile, defensive lineman Mykel Williams is expected to make his season debut after recovering from an injury, potentially bolstering San Francisco’s defense against one of the league’s top units. The outcome of this matchup could significantly impact standings in the NFC West division as both teams have undergone changes since their last meeting.
Written for “Nfl Injury Updates” on 2026-10-09,
grounded in this article and the 0 other(s) covering the same event.
The 49ers have several players dealing with injuries ahead of Sunday’s divisional matchup against the Seahawks.
asserted
49ers → have → Seahawks
While San Francisco currently leads the NFC West, the 49ers were absolutely crushed in their last meeting with Seattle in the NFC Divisional Round.
asserted
49ers → lead → Round
Both squads look different than last year, but there’s certainly plenty of bad blood between the division rivals.
asserted
squads → look → rivals
Here’s the latest update on a number of key 49ers players before Sunday’s game.
asserted
update → ’ → game
Mike Evans
Evans played through injury in the 49ers’ Week 4 win over the Broncos.
asserted
Evans → play → Broncos
Despite having broken ribs, the veteran wide receiver posted 76 yards on five receptions.
asserted
receiver → have → receptions
At Thursday’s practice, Evans was seen running on the side field in uniform.
asserted
Evans → see → uniform
While he didn’t practice with the team, he remained active which is an encouraging sign for San Francisco.
asserted
which → practice → Francisco
Evans was limited at practice Wednesday but his designated for Sunday’s game against the Seahawks is unclear, though the 49ers could certainly use his experience and finesse against one of the league’s best defenses.
uncertain
49ers → limit → defenses
Williams appears ready to make his season debut when the 49ers square off against Seattle at Lumen Field this weekend.
asserted
49ers → appear → Field
The defensive lineman is recovering from a torn ACL and lateral meniscus in his right knee, which he sustained in November 2025.
asserted
he → recover → November
Based on how he looked at Thursday’s practice, Williams should be ready to play in Week 5.
asserted
Williams → base → Week
Nick Bosa
Bosa has been dealing with a calf injury and is expected to miss his third consecutive game against the Seahawks as he recovers.
asserted
he → deal → Seahawks
He was seen working off to the side at Thursday’s practice.
asserted
He → see → practice
Christian McCaffrey, Trent Williams
McCaffrey and Williams both practiced Thursday after taking rest days on Wednesday.
asserted
McCaffrey → practice → Wednesday
The two offensive stars appear ready for the highly-anticipated Week 5 matchup against the Seahawks.
asserted
stars → appear → Seahawks
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