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Hayden Panettiere died from an accidental overdose involving fentanyl and other drugs on August 16 in Greenville, South Carolina. An autopsy revealed the toxic effects of fentanyl, 4-ANPP, alprazolam, methocarbamol, and quetiapine caused her death. The incident was reported by emergency responders after a call from Panettiere's boyfriend Brian Hickerson and his brother Zach. Police initially said there were no signs of foul play.
Written locally by qwen2.5:14b on 2026-09-22,
using this article's own text rather than the other coverage of the
same event (that is the story summary below).
Story summary
Hayden Panettiere, a 36-year-old American actress known for roles in TV shows like *Heroes* and *Nashville*, died from an accidental overdose involving multiple drugs, including fentanyl, on August 16 in Greenville, South Carolina. The Greenville County Coroner's Office ruled her death as an accident with no signs of trauma after conducting an autopsy. Drugs found in her system included fentanyl, 4-ANPP, Alprazolam (Xanax), Methocarbamol, and Quetiapine. Her on-and-off boyfriend Brian Hickerson and his brother Zach were present at the scene and made the 911 call. Panettiere's family described her as a "force of nature" who brought joy to millions.
Written for “Hayden Panettiere Cause Of Death” on 2026-10-05,
grounded in this article and the 15 other(s) covering the same event.
Actor
died from an accidental drug overdose that included fentanyl, a South Carolina coroner confirmed Tuesday.
asserted
coroner → die → fentanyl
Emergency responders were called to a residence where Panettiere had been staying in Greenville, South Carolina on the afternoon of August 16.
asserted
Panettiere → call → August
Despite "advanced cardiac life support measures," she was
there, the Greenville County Coroner's Office said.
asserted
Office → say → measures
An autopsy by the coroner's office found that Panettiere's death was accidental and ruled that the cause was the "toxic effects of" the drugs fentanyl, 4-ANPP, alprazolam, methocarbamol and quetiapine.
asserted
cause → find → drugs
There were no signs of trauma, the coroner's office said.
asserted
office → be → trauma
Panettiere's on-again, off-again boyfriend Brian Hickerson and his brother Zach were at the scene of her death, according to a
.
uncertain
boyfriend → accord → a
The Hickersons made the 911 call that brought first responders to the apartment.
asserted
that → make → apartment
The police report said Brian Hickerson showed officers "the bag of medication" that Panettiere was "currently on," but the list of substances was redacted.
asserted
list → say → substances
Zach Hickerson later told TMZ that Brian gave Panettiere , a medication that can reverse opioid overdoses, after they found her unconscious at the residence.
asserted
her → tell → residence
Authorities including the Drug Enforcement Administration were investigating the circumstances of Panettiere's death.
asserted
Authorities → include → death
Police previously said that a preliminary investigation "has not indicated any signs of foul play or suspicious circumstances."
asserted
investigation → say → play
She said she became addicted to alcohol and opioids as a teenager.
asserted
she → say → teenager
She also discussed addiction in her recent memoir, "This Is Me: A Reckoning," as well as describing her experiences with physical abuse,
and recovery.
asserted
This → discuss → abuse
Panettiere told CBS News' Gayle King in May that she hoped sharing her story would help others.
uncertain
sharing → tell → others
"I really wanted to share with the world that they don't have to be afraid.
asserted
they → want → world
That they can live their truth.
asserted
they → live → truth
They can be imperfect," she said in the interview.
asserted
she → say → interview
Asked how she was doing, she replied, "Still working on myself all the time.
asserted
she → ask → myself
I had a great therapist and I'm — I'm better, healthier than I've been in a long time.
asserted
I → have → time
This is a developing story and will be updated.
asserted
This → develop → ?
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