A 24-year-old woman who
of the TCS New York City Marathon had a rare condition called , her father said.
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father → have → condition
Steve Apa told The New York Times that his daughter Rachel had been texting him indicating that she was in pain earlier in the race.
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she → tell → race
Her mother was waiting at Mile 25, he said, but Rachel never made it to the milestone.
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Rachel → wait → milestone
She collapsed at Mile 24.
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She → collapse → Mile
A bystander administered CPR, race organizer New York Road Runners said, until medical staff from the organization took over.
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staff → administer → organization
A defibrillator was used, NYRR said, and she was transported by ambulance to a Mount Sinai hospital, where she died after further treatment.
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she → use → treatment
The New York City Office of the Chief Medical Examiner told CBS News that no final determination of cause of death has been made.
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determination → tell → death
NYRR also did not confirm her cause of death.
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NYRR → confirm → death
"We are deeply saddened by Rachel's passing following running in Sunday's race," the organization said in a statement.
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organization → sadden → statement
Here's what to know about rhabdomyolysis and its connection to intense exercise.
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Here → know → exercise
Rhabdomyolysis is a condition that occurs when muscle cells break apart and spill a protein called myoglobin into the blood, along with potassium and other salts.
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cells → occur → potassium
Too much myoglobin can damage the kidneys' filtration system, while high potassium can cause a deadly heart rhythm.
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potassium → damage → rhythm
Up to 50% of people with rhabdomyolysis develop a kidney injury.
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% → develop → injury
The condition is very rare: About 26,000 people in the United States are diagnosed with it each year, according to the Cleveland Clinic.
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people → diagnose → Clinic
Rhabdomyolysis and exercise
Rhabdomyolysis can happen after very intense exercise.
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Rhabdomyolysis → happen → exercise
A person is at higher risk if they're exercising in hot weather, while dehydrated or while sick.
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they → exercise → weather
To prevent exercise-induced rhabdomyolysis, athletes should build up their exercise tolerance slowly, especially after time off.
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athletes → prevent → time
They should also drink enough water, skip hard workouts when sick, and avoid alcohol and stimulants around times of intense exercise.
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They → drink → exercise
While rhabdomyolysis can be caused by exercise, more cases are caused by drugs and toxins.
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cases → cause → drugs
In rare cases, statins can cause rhabdomyolysis, especially when they are mixed with certain other medications.
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they → cause → medications
Infections like the flu and conditions including heat stroke and seizures can also cause it.
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Infections → include → it
Crush injuries can also result in rhabdomyolysis.
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injuries → result → rhabdomyolysis
The most common signs of rhabdomyolysis are muscle pain, weakness and dark urine that looks like tea or cola.
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that → look → tea
Some people may also feel feverish, sick to their stomach, confused or barely able to urinate.
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people → feel → stomach
The symptoms can range in severity, the Cleveland Clinic said.
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Clinic → range → severity
Symptoms usually develop within one to three days.
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Symptoms → develop → days
A person who develops sore muscles and dark urine after a hard workout should go to an emergency room as soon as possible.
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who → develop → room
that "prompt treatment can really make a huge difference."How is rhabdomyolysis treated?
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rhabdomyolysis → make → difference
Treatment for rhabdomyolysis starts with a blood test for the muscle protein creatine kinase.
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Treatment → start → kinase
Once the diagnosis is confirmed, doctors will give a patient large amounts of IV fluids, including electrolytes, to flush the myoglobin through the kidneys.
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doctors → confirm → kidneys
Potassium levels are also carefully monitored.
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levels → monitor → ?
Patients may need more treatment if their kidneys were damaged.
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kidneys → need → treatment
They may need dialysis if their kidneys fail or if their potassium stays high.
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potassium → need → dialysis
Patients may also receive physical therapy.
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Patients → receive → therapy
The Cleveland Clinic says patients without complications may feel better within a few weeks, but doctors may recommend waiting weeks or even months before resuming exercise.
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doctors → say → exercise